Italian National Research Council
(Consiglio Nazionale delle Ricerche)

CNR LOGO


LOGO PFITargeted Project on Ageing (Progetto Finalizzato Invecchiamento)

The Targeted Project on Ageing (Progetto Finalizzato Invecchiamento) was approved by the Committee of Ministers for Economic Planning, a sign of the social and political impact that the growing proportion of older persons in the population has on the life of nations. It will involve a vast number of both basic and clinical investigators in the CNR laboratories and research groups in the Universities together with the collaboration of local and regional authorities as well as important contributions from the private sector.

Age associated changes in physiological and social functions as well as the occurrence of diseases in these older italians will be documented under the rubric of five subproject areas.

At the conclusion of this major effort, the first such broad-based study in Europe, the Italian authorities will have available documentation of the quality of life and health or the lack thereof of their older citzens.

This farsighted program of research into the life patterns of the older people of Italy will involve 214 research units. Most of these are based in the Universities, with important contributions from the National Research Council's own laboratories and investigators in other researc institutions.

Structure and organization of the project

Director: Prof. Luigi AMADUCCI - Direttore I Clinica Neurologica dell'Università di Firenze
Tel. 055/432224 - Fax 055/413603

Administrative Direction: Via Tiburtina, 770 - 00159 Roma
Tel. 06/4075891 - Fax 06/4075827
e-mail: mc5516@mclink.it

Technical Direction: Area della Ricerca del CNR
Via Leone Pancaldo, 21 - 50127 Firenze
Tel. 055/4223341 - 4223985 - Fax 055/4224240
e-mail: dellasanta@server.area.fi.cnr.it

Main Projects

SubprojectdescriptionCoordinator
1
Gerontobiology
Recent advances in cellular and molecular biology allow us to understand and, hopefully, to control the deleterious aspects of ageing and to improve the quality of late life. Such a broad-side approach to the complexity of the biological processes of ageing necessarily involves a number of research group with expertise in varied experimental methodologies. Prof. Giuseppe ROTILIO
Dip. di Biologia
Università "Tor Vergata"
Via della Ricerca Scientifica - 00133 - Roma
Tel. 06/2025460
Fax 06/2025450
2
Italian Longitudinal Study on Ageing
Studying of a population of about 6.000 subjects, aged over 65, in the different regions of Italy over five years of the project will permit the evaluation of the range of both physiological and pathological changes in the population, and the correlation of these with known as well as postulated risk factors for central nervous system, cardiovascular, and endocrine and metabolic disorders. Prof. Guglielmo SCARLATO
Istituto clinica neurologica dell'Università di Milano - Ospedale Maggiore Policlinico
Via F. Sforza, 35 - 20122 Milano
Tel. 02/55184306 - 5466168
Fax 02/55013144 - 55190392
3
Ageing and endocrine-metabolic diseases: pathogenesis
This project addresses the pathogenetic mechanisms that determine the most important endocrine and metabolic diseases of later life; diabetes mellitus, osteoporosis and dyslipidemias. Studies of reproductive and sexual changes with age in both women and men are included. Prof. Guido POZZA
Ospedale San Raffaele - Direzione Scientifica
Via Olgettina, 60 - 20132 Milano
Tel. 02/26432837
Fax 02/26413774 - 2152536
4
Ageing of the sensory system and cognitive processes
In the project quantitative studies of visual changes with ageing will define more rational use of mechanical and electronic audio-visual aids, particularly for reading. Secondly, a diagnostic strategy will be developed and put in place to evaluate the hearding impairment of later life and to devise better interventions. Vestibular functions will be assessed.
An important component will be to develop neuropsychological and neurophysiological tests that can be used in studies of older persons and in individuals with cognitive impairments.
Prof. Corrado BALACCO GABRIELI
Policlinico Umberto I - Cattedra di Ottica Fisiopatologica - II Divisione Oculistica
00161 Roma
Tel. 06/490296 - 4457725
Fax 06/4457706
5
The ageing population: quality of the life and independence
The factors that contribute to a high quality of life and maintenance of independent living for older people will be examined. The insoghts gained from the examination of successful ageing will allow us to develop strategies to counteract the main stresses that interfere with functional autonomy, whether these be social, psychological, environmental or disease related. Prof. Pierugo CARBONIN
Policlinico Agostino Gemelli - Cattedra di Geriatria
Largo Gemelli, 8 - 00168 Roma
Tel. 06/3388546
Fax 06/3051911

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Created: Thursday 2 May 1996, 10.25.34 Last Updated: Thursday 3 May 1996, 23.25.11